I find the default keyboard shortcuts in Blender very frustrating. Here are a list of changes that I prefer, adapted from Nimble Collective’s excellent video tutorial.

Step 1.
File > User Preferences > Input > …

Step 2.
… Select With: Left

Step 3.
… 3D View:

• Rotate View: Alt-Left Mouse
• Move View: Alt-Middle Mouse / Alt-Cmd-Left Mouse
• Zoom View: Alt-Right Mouse

Step 4.
… View2D:

• Pan View: Alt-Middle Mouse / Alt-Cmd-Left Mouse
• Zoom 2D View: Alt-Right Mouse

Step 5.
… Image > Image (Global):

• View Pan: Alt-Middle Mouse / Alt-Cmd-Left Mouse
• View Zoom: Alt-Right Mouse

Step 6.
… Search Box: [loop select] > Mesh > Loop Select:

• Select: Double Click

Step 7.
File > Save Startup File